In vivo and in vitro experimental laboratory complex

Animal research facility and in vitro testing laboratory of the Medical University of Łódź

Animal research facility and in vitro testing laboratory of the Medical University of Łódź entitled to conduct biological research in vitro and in vitro, using animal models and cell lines. Our professional interest lies in the field of medical research, such as:

  • biochemistry
  • haematology
  • histopathology
  • medical genetics
  • blood clotting disorders,
  • surgery: general, oncological, experimental and endocrinological,
  • metabolism
  • toxicity
  • pharmacokinetics
  • toxicokinetics
  • behavioural studies.

Our research facility accepts orders from both commercial entrepreneurs and academics native to Medical University of Lodz as well as other universities and research units.

 

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The in vivo and in vitro experimental laboratory complex is entered in the registry of the National Ethics Committee operating at the Ministry of Science and Higher Education. We are figuring in the national registry of animal breeders and research facilities, respectively at positions 049, and 0061

Laboratory has the consent and permission of the Minister of the Environment on the contained use of GMOs and, since 2013, it may obtain transgenic mice. It is a registered genetic engineering institution.

Animal research facility and in vitro testing laboratory of the Medical University of Łódź has implemented a management system according to PN-EN ISO/ EC 17025:2005

Services offered by the in vivo and in vitro experimental laboratory complex:

Biological evaluation of medical devices, based on standards outlined in ISO 10993:

  • PN-EN ISO 10993-2:2006 (Animal welfare requirements)
  • PN-EN ISO 10993-3:2009 (Tests for genotoxicity, carcinogenicity and reproductive toxicity)
  • PN-EN ISO 10993-5:2009 (Tests for in vitro cytotoxicity)
  • PN-EN ISO 10993-6:2009 (Tests for local effects after implantation)
  • PN-EN ISO 10993-10:2011 (Tests for irritation and skin sensitization)
  • PN-EN ISO 10993-11:2009 (Tests for systemic toxicity)

We have a PCA accreditation for the following methods:

  • Tests for in vitro cytotoxicity MTT, XTT, NRU and CF tests
  • Tests for local effects after implantation
  • Tests for irritation and skin sensitization: Closed-patch test (Buehler test)
  • Other research projects concerning molecular mechanisms in the field of neurology, oncology, toxicology, experimental surgery, metabolic and behavioural studies (AnyMAZE, Morrisa water maze, fear conditioning, IntelliCage).
  • Breeding and husbandry of animals with immunodeficiency.
  • Contained use of GMOs animals.
  • Training courses in the field of experimental procedures on laboratory animals
  • Providing test equipment to companies and for projects.
  • Help in the design of experiments on animals and consultations in the course of completing the application to the Local Ethics Committee.

PERMISSIONS:

Genetic engineering institution

Laboratory has the status of the Institute for Genetic Engineering and consent of the Minister of the Environment on the issue of contained use of GMOs, which facilitates research on immunology and genetic diseases as well as cancer studies using genetically modified animals.

Compatibility with EU/2010/63 Directive

We are fully compatible with EU/2010/63 Directive and the amendment of the law on the protection of animals used for scientific or educational purpose.

Keeping SPF and IVC

We have infrastructure for the maintenance of (Specific Pathogen Free) animals in the regime of sanitary barrier and the housing of animals with reduced immunity (using Individually Ventilated Cage system IVC)).

Entity in ARiMR

The laboratory is an entity registered in the Agency for Restructuring and Modernisation of Agriculture authorized for the purchase and ownership of livestock (sheep, goats, pigs).

Entity in MNiSW

Our laboratory is listed in official Ministry of Science and Higher Education registry as an animal breeding unit, as well as an experimental facility designated to perform in vivo animal research..

In the Animal research facility and in vitro testing laboratory of the Medical University of Łódź, in accordance with Article. 25 of the Act of 15 January 2015 on the protection of animals used for scientific or educational purposes, we have elected an Advisory Body on animal welfare, the members of which are:

Jakub Fichna, Prof, MD

Kamila Bulak, MDVet

Jadwiga Komos, Eng. zootechnics

The tasks of the advisory team include, but are not limited to::

  • monitoring of animal welfare
  • counseling in the field of animal welfare
  • maintenance of internal rules of conducting with animals
  • monitoring of animals killing for the purpose of obtaining tissue for research
  • control over conducting experiments and their results
  • reporting of violations

Anna Rybicka, MDVet, supervises the personnel responsible for animal care and upkeep of the animals, she is also responsible for animal welfare and the organisation of training courses in accordance with the guidelines established by the abovementioned Act.

Contact:

Anna Rybicka, MDVet

Phone: 42 272 55 80

e-mail: anna.szalas@umed.lodz.pl; animal@umed.lodz.pl

 Justyna Malinowska, administrative-finalcial specialist

tel.: 42 272 55 89

e-mail: justyna.malinowska@umed.lodz.pl

Animal research facility and in vitro testing laboratory of the Medical University of Łódź

Muszyńskiego Street 1, 90-151 Lodz

The in vivo and in vitro experimental laboratory complex
Muszyńskiego Street, 90-151 Lodz