CIITT Uniwersytet Medyczny w Łodzi > Animal research facility. Services
  1. Keeping animals to research projects as well as own cultures.
  2. Biological evaluation of medical devices: genotoxicity, carcinogenicity and reproductive toxicity studies according to ISO 10993-3:
    • OECD 474 Mammalian Erythrocyte Micronucleus Test
    • OECD 475 Mammalian Bone Marrow Chromosome Aberration Test
    • OECD 478 Genetic Toxicity: Rodent Dominant Lethal Test
    • OECD 483 Mammalian Spermatogonial Chromosome Aberration Test
    • OECD 451 Carcinogenecity studies
    • OECD 453 Combined Chronic Toxicity/Carcinogenecity Studies
    • OECD 414 Prenatal Developmental Toxicity Study
    • OECD 415 One-generation Reproduction Toxicity Study
    • OECD 416 Two-generation Reproduction Toxicity Study
    • OECD 421 reproduction/ developmental toxicity screening test3
  3. Biological evaluation of medical devices: study of local effects after implantation according to ISO 10993-6:
    • subcutaneous implantation
    • intramuscular implantation
    • bone implantation
  4. Biological evaluation of medical devices: study of irritation and skin sensitization according to ISO 10993-10:
    • skin irritation
    • skin irritation
    • LLNA
    • GPMT
    • Closed-Patch test
    • Ocular irritation test
    • Penile irritation test
    • Rectal irritation test
    • Vaginal irritation test
  5. Biological evaluation of medical devices: systemic toxicity tests according to ISO 10993-11:
    • OECD 420 Acute toxicity
    • OECD 408 Subchronic toxicity
    • OECD 452 Chronic toxicity
  6. Cytotoxicity of a medical device in the form of an extract using in vitro assays: NRU, MTT, XTT, colony formation.
  7. Research projects in the field of neurology, orthopedics, toxicology, experimental surgery, oncology, metabolic and behavioral research (AnyMAZE, Morris pool, cage of fear, IntelliCage)
  8. Conducting studies using GMOs.
  9. Training in procedures on laboratory animals.
  10. Renting test equipment.
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